Inspect all new cartridges prior to use.
Allow the cartridge to come to room temperature and gently swirl, do not shake.
If the solution is cloudy or hazy or contains any solid matter, the cartridge should not be used.
Return the cartridge to your pharmacist or prescribing doctor.
1. Remove the green pen cap and unscrew the cartridge holder.
2. Press the white reset button.

3. Turn the black dose knob anticlockwise back to its starting position until it no longer tuns.

4. Turn the dose knob clockwise until the first click position is reached (1/4 turn)

5. Insert the NutropinAq cartridge into the cartridge holder and screw the cartridge holder back onto the pen. Be careful not to touch the rubber seal.

6. Screw the needle assembly onto the cartridge holder. Remove both protective caps from the needle by pulling gently. Retain the larger cap for later use.

7. With the pen in the upright position and the needle pointing upwards, gently tap the cartridge holder to move any air bubbles to the top.

8. Still holding the pen upright, push in the black dose knob until it clicks. A drop of medicine should appear at the needle tip.

9. If no drop of medicine appears, push the white reset button, turn the black dose knob clockwise by one click, and push the dose knob in again.
Watch for a drop of medicine to appear. Repeat steps 8 and 9 until a drop of medicine does appear.

10. Press the white reset button. The LCD will blink for 5 seconds.

11. Set the required dose by turning the black dose knob. If you turn the dose knob too far, you can turn it back to achieve the correct setting.

12. The needle shields hide the needle when you inject, protecting it from damage. If you are using the passive shield or no shield, go to step 13.
If you are using the active shield, slide the shield onto the pen and push the two black lock knobs on the needle shield towards the tip.

13. Prepare the injection site by wiping it with an alcohol swab. Injection sites include upper arms, abdomen and upper thighs. Change the injection sites to avoid discomfort.

14. Set the tip of the pen on the prepared injection site and press the needle into the skin by pushing downward until the shield is totally depressed. Press down on the black dose knob. Wait 5 seconds, then withdraw the pen from the skin.

15. Pull the needle shield off the pen (if you have used one) and place the larger needle cap on a flat surface. Slide the needle in to pick it up and push the cap completely down over the needle. Twist off the needle and discard it appropriately in a sharps disposal container. Always store your disposal container out of reach of children.

16. Attach the pen cap and return it to its case with the black dose knob pressed in. Store your pen in the refrigerator (between 2-8°c). Do not remove cartridge between injections.
